Creative Biogene is a professional C. elegans model service provider. We are dedicated to providing our customers with high-quality data delivery, in-depth scientific and technical support.
C. elegans Genetic Services
Caenorhabditis elegans has served as a powerful model organism for genetic and genomic analysis due to its unique characteristics and numerous experimental advantages. To facilitate the research that utilizes C. elegans, we provide C. elegans genetic services, including genetic engineering service and chemical mutagenesis service, to design, build and deliver genetically engineered worms for our customers. More details
C. elegans Stress Response Model Services
Stress in C. elegans affects genes and pathways that share a high homology with humans and play an important role in various complex diseases. Here we exploit C. elegans stress response models to provide insight into the mechanism underlying human disease and access to potential targets for drug discovery. The stress response model refers to oxidative stress, heat stress, osmotic stress and hypoxia, cold tolerance, UV stress, heavy metal stress.
C. elegans Drug Screening Services
C. elegans has been used for drug screening since 1973. A number of traits, including genetic and molecular tractability, amenability to high-throughput screening methods, experimental cost-effective and fast turnaround, make the worm a valuable model organism for drug discovery. Herein, we use advanced technologies and optimized protocols to help customers conduct drug screening, including anti-infective compounds, drugs against neurodegenerative diseases, pro-longevity compounds, and anti-cancer drugs. We also customize drug screening pipelines to satisfy our customers' every need.
C. elegans Biological Detection Services
We also provide a series of C. elegans biological detection services, including the membrane fluidity assessment, quantification of bacteria in intestine, oxygen consumption rates measurement, lysosomal detection, collagen deposition assessment, and cuticle isolation.
C. elegans Aging Research Services
Aging has long been a concern. The research involved in aging gene expression and multiple pathways has been widely studied and reported. Here we offer a series of measurements of age-associated changes that serve as aging biomarkers indicative in C. elegans to provide information for aging research, therefore, providing great convenience for our customers.
C. elegans DNA Methylation Analysis Services
With the recent advent of more sensitive detection techniques, a major type of DNA methylation, N6-methyldeoxyadenine (6mA) has also been detected in C. elegans. We offer DNA methylation analysis services that provide information on 6mA in C. elegans from different perspectives, including preliminary analysis, 6mA quantification by UHPLC-MRM-MS, and conjoint sequencing analysis.
Given that C. elegans is an extremely versatile model system and widely used in genetic mechanisms, energy metabolism, immunity, aging and screening studies, we offer comprehensive and systematic services that contribute to the better use of C. elegans for researchers.